ionchannel相关论文
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General anesthesia is an unconscious state induced by anesthetics for surgery.The molecular targets and cellular mechani......
During the last decade,transient receptor potential (TRP) channels emerge as key proteins in central mechanisms of the c......
Recently,the ion motion system has attracted a lot of attention,not only as bio-functional materials but also for develo......
The NCX1/TRPC6 Complex Mediates TGFb-Driven Migration and Invasion of Human Hepatocellular Carcinoma
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In vitro neural differentiation of human umbilical cord blood-derived mesenchymal stem cells induced
Human umbilical cord blood-derived mesenchymal stem cells(UCB-MSCs)could be induced to differentiate into neural cells u......
Aim: To investigate the antiarrhythmic mechanism of taurine magnesium coordination compound (TMCC) on sodium current (IN......
Various recent studies showed that postsynaptic density(PSD)scaffold proteins Shank involved in autism,schizophrenia and......
Circadian Regulation of Cardiac Sodium-Calcium Exchanger in Response to Physiological and Pathophysi
Aim:This study was designed to investigate rhythmic expression of NCX1 and circadian clock genes as well as their interf......
Chronic exercise normalizes changes of CaV1.2 and KCa1.1 channels in mesenteric arteries from sponta
Regular physical activity is an effective non-pharmacological therapy for prevention and control of hypertension.However......
Purpose Safety pharmacology(SP)is essential for the drug development,which aims to identify adverse effects of a new dru......
Reduced Expression of FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) in Association with H
Background To investigate the expression of hypertension-related genes in spontaneous hypertension.Methods A microarray ......
Effects of taurine magnesium coordination compound on INa,ICa,L and Ito in rat ventricular cardiomyo
OBJECTIVE To investigate the antiarrhythmic mechanism of taurine magnesium coordination compound (TMCC) on sodium curren......
Ion channels are critical for the normal physiological function of the organism.The functional abnormality of the ion ch......
Regulating effects of TongXie-YaoFang formula on colonic epithelial secretion in rats with diarrehea
AIM To investigate the pharmacological effect of TongXie-YaoFa ng(TXYF) formula on Diarrhea-predominant irritable bowel ......
Circadian Regulation of Cardiac Sodium-Calcium Exchanger in Response to Physiological and Pathophysi
Aim This study was designed to investigate rhythmic expression of NCX1 and circadian clock genes as well as their interf......
Profiling of ion channel gene expression in dorsal root ganglion during nerve injury and inflammator
The increased pain sensation during nerve injury and inflammation results from several mechanisms.Alteration of Ion chan......
Adverse drug side effect, such as cardiotoxicity, is a major concern in drug development and a major cause of drug withd......
Dorsal root ganglia (DRG) contain cell bodies of peripheral nerve fibres conveying somatosensory inputs to the CNS.Somat......
Ethanol is a chemical irritant that generates a"burning" sensation; the heat-sensitive TRPV1 ion channel is the recept......
Ontogeny of neuronal excitability of vagal afferent/baroreceptor neurons and its ion channel mechani
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Biological ion channels play an important role in the functioning of cell or living organism,which can open and close in......
With self-fields and betatron oscillation characteristics taken into account,dispersion characteristics of two families ......
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Physical properties of relativistic electron beam during long-range propagation in space plasma envi
It is known that ion channel can effectively limit the radial expansion of an artificial electron beam during its long-r......
Age-related changes in dispersion of atrial effective refractory period and its ionic mechanism in c
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机械转导是细胞功能的一项基本机制，在人类生长发育、生理及病理过程中具有关键作用，其分子机制一直是研究热点。Piezo2蛋白是一种机......
We will show our continuum(or implicit solvent)finite element/boundary element molecular modeling approaches in comp......
The flow of current through an ionic channel is studied using the energetic variational approach of Liu applied to t......
Exploring the Gating Mechanism of the Calcium Release-Activated Calcium Channel with Molecular Dynam
Calcium release-activated calcium(CRAC)channels in the plasma membrane are integral membrane proteins that is critic......
The family of cyclic nucleotide-regulated ion channels includes the cyclic nucleotide-gated (CNG) channels, the hyperpol......
MicroRNA (miRNA) alterations in response to changes in an extracellular microenvironment have been observed and consider......
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目的：研究树鼩脑缺血及缺血后适应（postconditioning，PC）对酸敏感性离子通道（acid－sensing ion channel，ASIC）2a表达及海马微环境离子稳态......
Genetic defects associated with profound increases rnin Q-TC have frequently been associated with either rna reduction i......
Ca2＋-钙调蛋白依赖性蛋白激酶Ⅱ是一种分布广泛的多功能丝氨酸／苏氨酸蛋白激酶，参与调节心脏的多种生理活动，如兴奋-收缩耦联和兴奋-转......
肺动脉高压是一组进展性的、预后极差的恶性心脏疾病，本病以肺血管重构，肺血管阻力升高，最终导致右心衰竭为特点。最近5年，随着对肺动......
目的通过比较对不同跨膜离子电流作用的效能、效价,探讨传统中药苦参碱抗心律失常作用弱于西药奎尼丁、维拉帕米的原因,确定苦参碱......
A new viewpoint and model of neural signal generation and transmission:Signal transmission on unmyel
We establish a preliminary model of neural signal generation and transmission based on our previous research,and use thi......
本文对各种条件下离子通道的建立及其暂态变化特征进行了研究 ,对影响其特性的因素进行了讨论 ,并用著名的粒子模拟软件MAGIC对其......
较高密度的相对论电子束注入等离子体中将会形成离子通道，在考虑了离子通道的影响下，推导出圆柱波导中更普遍的色散方程，并计算出考虑......
